Consistently linked with exposure at relevant levels of exposure with confounding and background exposures assesseda Effect Consistently linked with increased risk with confounding and effect modifying factors assessed Susceptibility Can distinguish subgroups at risk given specific exposure a Biomarkers of exposure may also be validated by establishing a constant link to an adverse health effect or to the concentration of the chemical in the target organ. This applies to any form of exposure. It is due to intervening host factors that vary between individuals such as breathing rate and capacity, activation, detoxification, elimination, DNA repair, etc. Thus a high correlation between exposure and the marker may not always be observed and an exposure-response relationship may vary between people.
Following his doctoral studies he joined Janssen Pharmaceutica. He served as dean of his faculty between and Since he is a member of the Board of Directors of Ghent University. Later, he was member of the CDF collaboration that discovered in the top quark, one of the 12 elementary particles that constitute matter.
Inhe comes back to CERN in order to perform research on radiation detectors in the groups of F. When he returned to Spain inhe started a research group on Medical Imaging. Since then, he has developed several medical imaging devices based on the detection of gamma rays, X-rays, and magnetic resonance, that have been successfully transferred to industry for instance, BRUKER and installed in the best research and medical centers of the World.
Author of around articles in international peer reviewed publications, with an H index of Advisor of 10 PhD theses. Author of more than 20 patents related to imaging equipment for medical diagnosis. He earned his Ph. He has worked on multiscale numerical methods, domain decomposition methods, stabilized finite element methods, and, more recently, on isogeometric analysis efficient solvers, unstructured isogeometric spaces, isogeometric differential forms, She has been the head of the Applied Maths Department at Ecole polytechnique from to Award La Recherche He obtained a Ph.
He was a lecturer at the University of Texas at Austin They constitute the basic language in which most of the laws in physics or engineering can be written and one of the most important mathematical tools for modelling in life and socio-economical sciences.
More precisely, his expertise comprises long-time asymptotics, qualitative properties and numerical schemes for nonlinear diffusion, hydrodynamic, and kinetic equations in the modelling of collective behaviour of many-body systems such as rarefied gases, granular media, charge particle transport in semiconductors, or cell movement by chemotaxis.
He was the chair of the Year of Mathematical Biology. He is editor in more that 15 journals in PDEs and their applications. He received his diploma in electrical and mechanical engineering from the National Technical University of Athens, Greece, in and the M.
His research interests are in stochastic control, manufacturing, sustainability and climate change. Phillis is member of the editorial board of several technical journals. He has published over scientific papers, six technical books, and fifteen poetry collections and novels.
He is an award winning writer in Greece and the US. He obtained his PhD at the same university in the group of Prof. Ahmed Zewail, and returned in to his alma mater.
He has a strong interest in nanochemistry and supramolecular chemistry on surfaces.
Molecular self-assembly on surfaces is a central theme of his research, with a focus on the relation between structure and function. Recent research activities cover a broad range of topics such as two-dimensional crystal engineering e.
The liquid-solid interface is his preferred research environment. He also investigates biomolecular systems DNA, proteins, their complexes, etc. Scanning probe microscopy and spectroscopy techniques are particularly useful in this respect. He was awarded an Advanced ERC grant in He is Fellow of the Royal Society of Chemistry.
He created a research team dedicated to non-crystalline solids in the early years of his career. Dubois was the founding and first director of Institut Jean Lamour in Nancy, the largest public research laboratory dedicated to materials science and engineering in France.Lab 6: Electrophilic Aromatic Substitution(1) Nitration of Methyl Benzoate(2) Synthesis of 1,4-Di-t-butyl-2,5-dimethoxybenzene byFriedel-Crafts Alkylation of 1,4-DimethoxybenzenePurpose1)To carry out the nitration of methyl 4/5(2).
Methylene chloride is a chlorinated hydrocarbon that has been used as an inhalation anesthetic and acts as a narcotic in high concentrations.
Its primary use is as a .
Electrophilic Aromatic Substitution Formal Lab Objective: The objective of this experiment was to form p-Nitroacetanilide and o- Nitroacetanilide by an electrophilic aromatic substitution.
Synthetic Equation: Procedure: The nitrating reagent was prepared by slowly adding ml of cold concentrated sulfuric acid to ml of cold concentrated nitric acid in a 50 mL Erlenmeyer flask. Essay Electrophilic Aromatic Substitution Formal Lab Electrophilic Aromatic Substitution Objective The objective of this experiment was to illustrate electrophilic aromatic substitution by synthesizing p-nitroanilide (as well as ortho) from acetanilide by nitration.
AET Internal Combustion Engine Theory and Servicing. This is a theory/laboratory course designed to introduce the student to basic heat engine types, their .
Aromatic compounds can undergo electrophilic substitution reactions. In these reactions, the aromatic ring acts as a nucleophile (an electron pair donor) and reacts with an electrophilic reagent (an electron pair acceptor) resulting in the replacement of a hydrogen on the aromatic ring with the electrophile.